Ali 'Imran 3:96

Inna awwala baytin wudiAAa linnasilallathee bibakkata mubarakan wahudan lilAAalameen

Indeed, the first House [of worship] established for mankind was that at Bakkah [i.e., Makkah] - blessed and a guidance for the worlds.

The first house set up for the people is surely the one in Makkah having blessings and guidance for all the worlds.